- Dr. Carlos F. Gonzalez
- Professor, Plant Bacteriology
- Rm. N313, Biochemistry Annex
- Graduate Education
- Ph.D. Plant Pathology, University of Nebraska-Lincoln, 1978
- Courses Taught
- PLPA 301 Plant Pathology
- BESC 401 Bioenvironmental Microbiology
Research in my laboratory encompasses a range of studies that address the genetics of virulence and pathogenicity. The model systems used in our studies are members of the Burkholderia Cepacia Complex (BCC) composed of nine species. The BCC are recognized as significant pathogens in cystic fibrosis patients. We are currently studying secretion systems responsible for export of a cytotoxic protein(s) in both B. cepacia (plant pathogen) and B. cenocepacia (human pathogen) to determine common mechanisms for pathogenicity. In addition we are conducting genomic analysis of BCC bacteriophage.
Gonzalez, C. F., E. A. Pettit, V. A. Valadez, and E.A. Provin. 1997. Mobilization, cloning, and sequence determination of a plasmid encoded polygalacturonase from a phytopathogenic Burkholderia (Pseudomonas) cepacia. Mol. Plant-Microbe Interactions: 10:840-851.
LiPuma, J. J, T. Spilker, T. Coenye and C. F. Gonzalez.2002. Identification in soil of an epidemic Burkholderia cepacia complex strain. Lancet 359:2002-2003.
Gonzalez, C. F., E.M. Provin, L. Zhu, and D. J. Ebbole. 2002. Independent and synergistic activity of synthetic peptides against thiabendazole resistant Fusarium sambucinum. Phytopathology 92: 917-924.
Summer, E., C. F. Gonzalez, T. Carlisle, L. M. Mebane, A. M. Cass,C.G. Savva, J. J. LiPuma and R. Young. 2004. Burkholderia cenocepacia phage BcepMu and a family of Mu-like phages encoding potential pathogenesis factors. J. Mol. Biol. In Press
Engledow,A. S., E.G. Medrano, E. Mahenthiralingam,J. J. LiPuma and C.F. Gonzalez. Involvement of a Plasmid Encoded Type IV Secretion System in the Plant Tissue Watersoaking Phenotype of Burkholderia cenocepacia Submitted to J. Bacteriology