Department of Plant Pathology and Microbiology Texas A&M University
Daniel J. Ebbole
Professor

Office:
321B LF Peterson

Phone:
979-845-4831

Email:
d-ebbole@tamu.edu

Daniel J. Ebbole
Education

Ph.D. Biochemistry (1988)
Purdue University

Research Emphasis:

Fungal Molecular Biology

My research interest is in fungal genetics, focusing on development and pathogenesis. A major focus of the program is functional genomic analysis of the rice blast fungus. I am a co-PI involved in a multi-institutional NSF Plant Genome Project for functional analysis of the rice-M. grisea interaction. Our role in the project is functional characterization of secreted proteins to explore their interactions with plants. The signal transduction pathways controlling pathogenesis also regulate developmental processes. Thus, a basic understanding of signal transduction has relevance for plant pathogens. Our second research area is exploring developmental processes in Neurospora crassa, a model genetic system.


Teaching

PLPA 611: Advanced Plant Pathology (3 hr). This course is required of all graduate students entering the Department and introduces students to the science of plant pathology.

PLPA 689: Advanced Plant Pathology Laboratory (1 hr). This laboratory is associated with PLPA611 and consists of laboratories that showcases many areas of plant pathology that are represented by research programs in our Department.

PLPA 625: Plant Pathogenic Fungi (3 hr with 1 hr lab). This course provides an overview of fungal biology from mycology to genomics.


Recent Publications

Dean RA, Talbot NJ, Ebbole DJ, Farman ML, Mitchell TK, Orbach MJ, Thon M, Kulkarni R, Xu JR, Pan H, Read ND, Lee YH, Carbone I, Brown D, Oh YY, Donofrio N, Jeong JS, Soanes DM, Djonovic S, Kolomiets E, Rehmeyer C, Li W, Harding M, Kim S, Lebrun MH, Bohnert H, Coughlan S, Butler J, Calvo S, Ma LJ, Nicol R, Purcell S, Nusbaum C, Galagan JE, Birren BW. Related Articles, Links Abstract The genome sequence of the rice blast fungus Magnaporthe grisea.
Nature. 2005 Apr 21;434(7036):980-6.
PMID: 15846337 [PubMed - indexed for MEDLINE]

Li D, Bobrowicz P, Wilkinson HH, Ebbole DJ. Related Articles, Links
Free Full Text A mitogen-activated protein kinase pathway essential for mating and contributing to vegetative growth in Neurospora crassa.
Genetics. 2005 Jul;170(3):1091-104. Epub 2005 Mar 31.
PMID: 15802524 [PubMed - in process]

Rerngsamran P, Murphy MB, Doyle SA, Ebbole DJ. Related Articles, Links
Abstract Fluffy, the major regulator of conidiation in Neurospora crassa, directly activates a developmentally regulated hydrophobin gene.
Mol Microbiol. 2005 Apr;56(1):282-97.
PMID: 15773996 [PubMed - indexed for MEDLINE]

Ebbole DJ, Jin Y, Thon M, Pan H, Bhattarai E, Thomas T, Dean R. Related Articles, Links Abstract Gene discovery and gene expression in the rice blast fungus, Magnaporthe grisea: analysis of expressed sequence tags.
Mol Plant Microbe Interact. 2004 Dec;17(12):1337-47.
PMID: 15597739 [PubMed - indexed for MEDLINE]

Xie X, Wilkinson HH, Correa A, Lewis ZA, Bell-Pedersen D, Ebbole DJ. Related Articles, Links Abstract Transcriptional response to glucose starvation and functional analysis of a glucose transporter of Neurospora crassa.
Fungal Genet Biol. 2004 Dec;41(12):1104-19.
PMID: 15531214 [PubMed - indexed for MEDLINE]

Bailey-Shrode, L., and D.J. Ebbole. 2004. The fluffy gene of Neurospora crassa is necessary and sufficient to induce conidiophore development. Genetics 166:1741-1749.

Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read ND, Jaffe D, FitzHugh W, {63 authors omitted}, Ebbole DJ, Freitag M, Paulsen I, Sachs MS, Lander ES, Nusbaum C, Birren B. 2003. The genome sequence of the filamentous fungus Neurospora crassa. Nature. 422:859-68.

P. Bobrowicz, R. Pawlak, A. Correa, D. Bell-Pedersen, and D.J. Ebbole. 2002. The Neurospora crassa pheromone precursor genes are regulated by the mating type loci and the circadian clock. Mol. Microbiol. 45:795-804. Abstract - PubMed

Z.A. Lewis, A. Correa, C. Schwerdtfeger, K.L. Link, X. Xie, H.R. Gomer, T. Thomas, D.J. Ebbole and D. Bell-Pedersen. 2002. Overexpression of WHITE COLLAR-1 (WC-1) activates circadian clock-associated genes, but is not sufficient to induce most light-regulated gene expression in Neurospora crassa.Mol. Microbiol. 45:917-931. Abstract - PubMed

A. Wiest, D. Grzegorski, B-W. Xu, C. Goulard, S. Rebuffat, D. J. Ebbole, B. Bodo and C. Kenerley. 2002 Identification of peptaibols from Trichoderma virens and cloning of a peptaibol synthetase. J. Biol. Chem. 277:20862-20868. Abstract - PubMed